The Classic and Autofill Compact and Benchtop autoclaves can be used for small quantities of non-hazardous discard. For larger, difficult loads a vacuum system is beneficial. If BSL3 (Cat3) waste is being sterilized, a heated jacket in addition to vacuum, would be recommended, since this ensures improved temperature distribution within the chamber. 12 point validation to a recognised standard is recommended to ensure that all parts of the load are being sterilized.